doc. Ing. Miroslav Soos, Ph.D. (group leader)

He studied at Slovak University of Technology, Slovakia where in 1997 he received master degree in Chemical Engineering and Process Control and in 2001 the PhD degree in Chemical Engineering. From 2001 till 2015 he was working at ETH Zurich, Switzerland initially as postdoctoral researcher and later as Senior Research Scientist. During this period he was involved in several research projects related to colloidal engineering, modeling of fluid dynamics using CFD and synthesis of advanced functional materials. He was responsible for development of patented method for production of porous nano and microparticles as well as for establishment and leadership of the cell culture laboratory dedicated to production of therapeutic proteins. In 2015 he joint UCT Prague where he is currently leading Biotechnology and Advanced Functional Material Laboratory. His interest covers synthesis of various nanoparticles and their assembly towards functional materials which can find application as conductive polymers, sensors, catalyst supports, stationary phases for separations, drug delivery systems and API formulation processes.

Mgr. Fatima Hassouna, Ph.D. (senior scientist)

Fatima Hassouna is an Assistant Professor at the Department of Chemical Engineering at the Faculty of Chemical Engineering at the University of Chemistry and Technology, Prague (UCT Prague). In 2003, she was awarded with a scholarship from the French Ministry of National Education and Research for the support of her Ph.D. work at Laboratoire de Photochimie Moléculaire et Macromoléculaire (LPMM). She obtained her Ph.D. degree in Physical Chemistry of Polymers in 2006 from the University of Blaise Pascal (France). She then went on to do postdoctoral studies at the École Nationale Supérieure de Chimie de Clermont-Ferrand and at the research and development center of Arkema Inc. in King of Prussia, PA, USA During her post-doctoral stay she worked on the development of a new technology based on “supramolecular modification of PMMA” using radical polymerization and using reactive extrusion. Read more...

After her post-doctoral stay, she was hired as a permanent R & D researcher by Centre de Recheche Public Henri Tudor that became Luxembourg Institute of Science and Technology Grand-Duché de Luxembourg). She was in charge with the topics related to the chemical modification and synthesis of polymer-based (nano)-composites issued from renewable resource using reactive extrusion processing and polymer synthesis and the topics related to material ageing (UV, thermal, hydrolytic, biodegradation…).

In 2015 she joined Bioengineering and Functional Materials Laboratory as a senior researcher and assistant professor at the Department of Chemical Engineering at UCT Prague. Her research interests focus mainly on:

  1. Synthesis and chemical modification of polymers (biobased polymers, acrylic polymers…) for different applications such as packaging, automotive, pharmacy.
  2. Synthesis and chemical modification of nanofillers such as cellulose nanocrystals, graphene materials, nanoclay, iron oxide… for preparation of highly compatible (nano)-composites.
  3. Polymer processing for preparation of high performance polymeric materials and (nano)-composites using different processing techniques such as hot melt extrusion, compression molding, injection molding, solvent casting, spin-coating, emulsification, nanoprecipitation.
  4. Physical properties (morphological, thermal, mechanical, rheological, electrical, gas barrier…) and physical chemistry of the polymeric materials such as prediction of solubility/miscibility and interaction parameters of API with polymeric matrices.

Ing. Eliska Skorepova, Ph.D.

She studied the field of ‘Synthesis and Production of Drugs’ at the University of Chemistry and Technology in Prague. She specialized in the solid phase characterization of active pharmaceutical ingredients at the Department of Solid State Chemistry. In 2016, she defended her PhD thesis titled ‘Preparation and Structural Characterization of Novel Solid Forms of Pharmaceutical Ingredients Trospium Chloride and Agomelatine’, which was done in cooperation with a pharmaceutical company Zentiva, k.s. She has experience with the crystallization of new solid phases of pharmaceuticals utilizing various solid-state analytical techniques (e.g. X-ray diffraction), interpretation and analysis of powder and single-crystal data, calculation of the crystal lattice energy, molecular and quantum mechanics. Now, she is a junior researcher in doc. Soos’s group and focuses on the crystal engineering in the pharmaceutical development.

PhD students
Ing. Vitek Zvonicek

Vitek has obtained his Masters degree at UCT Prague in the study programme "Synthesis and Production of Pharmaceuticals" with the main focus on an organic synthesis. His previous background also included chemistry education, as he studied Masaryk High School of Chemistry in Prague. Currently, Vít study a PhD programme "Drugs and Biomaterials" at the Faculty of Chemical Engineering at UCT Prague. His main focus is the solid state of a pharmaceutical ingredients. During his studies, starting at master level, he cooperates with a pharmaceutical company Zentiva, where he participates on the research of the solid state of pharmaceuticals for generic drug products. In a recent, he started to cooperate also with Department of Physics of the Czech Academy of Sciences, where he participates on a project focused on a behavior of multicomponent solid forms of (mostly) pharmaceuticals. Overall, Vít has the main skills in organic synthesis, crystal engineering and solid state analysis, including X-ray (single crystal and powder) diffraction technique, spectroscopies (Raman, NMR, IR) and thermal techniques such as DSC, TGA and Hot-Stage microscopy.

M.Sc. Edith Mawunya Kutorglo

Edith holds an Erasmus Mundus Joint M.Sc. in Membrane Engineering and a B.Sc. (Honours) in Biochemistry. With a background in Material Science and Nanotechnology and having worked as a research intern in two institutions – Noguchi Memorial Institute for Medical Research, Accra-Ghana and MemBrain s.r.o. Czech Republic, Edith gathered a unique experience in biochemical engineering techniques, nanoparticle synthesis, design of nanostructured materials and their characterization. For her master thesis, Edith worked at the Nanostructured and Tuneable Materials Lab, University of Bath, in the UK, where she focused on developing electrically tuneable membranes from intrinsically conducting polymers (ICPs). Fascinated by the unique behavior of the ICPs, her current research focuses on the development of functional macroporous materials by controlled assembly of core-shell type nanoparticles prepared from ICPs. She is particularly interested in understanding the correlation between the molecular structure and properties of these materials and how they can be engineered for optimum performance in applications such as CO2 capture, catalysis and biosensors.

MSc. Argyro Chatziadi

Argyro has obtained her B.Sc. and M.Sc. degree at the Department of Material Science, at University of Patras, in Greece, in the field of Material Science.As a student she investigated the modification of glasses with silanes with different final groups and she studied the adhesion of bacteria on them under flow conditions. During her M.Sc. her project was a theoretical and computational study of packaging and ejection of macromolecular chains within spherical nano-containers. Also during her Master she decided to work as an Erasmus student at the University of Twente, in a three months project about synthesis of building blocks to form self-assembled amphiphiles, for future drug delivery applications. Furthermore, she worked as a Marie Skłodowska-Curie fellowship partner (ESR) at the department of Chemical and Pharmaceutical Sciences, at University of Trieste. Her project was about functionalization of carbon nanotubes and fullerenes. Her main research interests are: Crystal Engineering, Nanotechnology, Biomaterials.

Argyro’s research project now is focused on the development of a combined computational and experimental methodology for efficient screening of co-crystals and solvate forms of active pharmaceutical ingredients. Her project is in cooperation with the pharmaceutical company Zentiva, k.s.

Ing. Jose Francisco Wilson Collao

He studied at Pontificia Universidad Católica de Chile, where received the title of Civil Engineer with a diploma in Geotechnical Engineering. In 2016, he obtained the degree of Master in Engineering Sciences. During his studies he had several abroad experiences in USA and Portugal. In Boston, he collaborated as visitor student at the rock mechanics laboratory at Massachusetts Institute of Technology (MIT). Then, he studied one semester abroad at the Instituto superior Tecnico of Lisbon, where he focused on Civil Engineering design (Tunnels, Foundations, Concrete structures). After, he worked as a research Engineer at Stanford Research Institute (SRI International), where he collaborated to the development of tele-operated robotic equipment for mining blasting operations. Later, he worked as Engineer at a Mining Blasting company where acquired some experience related to detonators, high explosives and explosive emulsions. Some of his academic work has been focused in the modelling of granular media and the mechanical characterization of these materials under dynamic conditions (Geotechnical Earthquake Engineering). Nowadays, the research focus of Jose Francisco the numerical modelling of particles interaction, including its interaction with fluids.

Ing. Martina Jezkova

Martina graduated in bachelor program Nano- and Micro-Technology in Chemical Engineering from University of Chemistry and Technology in Prague (passed with honours in June 2015). Her bachelor thesis was focused on Density Functional Theory (Adsorption Behaviour of Model Polymers: A Microscopic Approach) under the supervision of doc. Alexandr Malijevský, Ph.D. at the Department of Physical Chemistry.Then, she continued with Chemical Engineering and Bioengineering master program, which she passed with honours in June 2017. In Bioengineering and Advanced Functional Materials Laboratory, she deals with the Synthesis of Gold Nano-Clusters. Martina defended this topic during final exams and she won second place twice, presenting this work, at the Student Scientific Conference (2015 and 2016). Martina is studying a Ph.D. program Chemical Engineering at the Department of Chemical Engineering since 2017. The goal of her work (Synthesis of Nano-Clusters for Controlled Release of Drugs) is preparation of various types of nanoparticles and subsequent combining them with porous materials loaded with drugs and with suitable surface modification. The product will be an active drug nano-carrier for both drug delivery and other therapeutic function (for example photothermal therapy).

M.Sc. Ioannis Vasilopoulos

Yannis’ Ph.D. research is focused on the mathematical modeling of crystallization processes covering crystal size distribution, shape as well as their composition. The latter is particularly crucial in crystal solvates’ formation observed for various Active Pharmaceutical Ingredients (APIs). In addition, he is involved with the in-silico modeling of the solvent diffusion through the crystal solvate structure. His project liaises with experiments, aiming to accurately understand, model and predict unit operations in the API-solvates synthesis including crystallization, filtration, and drying.

Yannis holds a B.Sc. in Physics from the Department of Physics and an M.Sc. in “Process Optimization, Simulation and Control” from the Department of Chemical Engineering, both from the University of Patras, Greece (GR). His research has been focused on phenomena associated with the dynamics of multiphase flows, interfacial fluid flows, biological flows and phase separation processes by using computational techniques. Read more...

Firstly, as an intern in the National Center for Scientific Research (NCSR) “Demokritos”, Athens, GR, he was involved with a research project regarding the patient-specific modeling of blood flow in a human aortic arch. Subsequently, he continued working in developing CFD models for simulating bio-flows for his bachelor thesis. Furthermore, during his postgraduate studies, he participated as a research fellow in the Laboratory of Fluid Mechanics & Rheology. He, then, developed both physical models and numerical algorithms for computing two-phase fluid flows with diffuse-interface methods, delivered under the financial support of postgraduate research fellowships granted by EU & Greek funds. After his graduation, he worked as a research fellow in the Laboratory of Thermal Hydraulics and Multiphase Flow, NCSR “Demokritos”, Athens, GR. His latest work concerned the patient-specific modeling of nanoparticles-blood flow in the abdominal aortic aneurysm under fluid-structure interaction conditions.

Research Interests: The development of numerical algorithms for studying both the physics of fluids/soft matter and transport phenomena, including multiscale modeling and concepts of various scientific orientations.

M.Sc. Alma Lucía Villela Zumaya

Alma obtained her bachelor degree in Chemistry from Instituto Tecnológico y de Estudios Superiores de Monterrey in Monterrey, Mexico. After that she got her M. Sc. in Nanochemistry from the Université Grenoble Alpes in Grenoble, France in 2016. Her master thesis was focused on the development of multifunctional nanoparticles as probes for cancerous cells based on solid state chemistry. After that she did an intenship at Insitut Néel in Grenoble for the topic of synthesis and characterization of a new generation of luminophors for solid state white lightning where she was focused on the optimization of YAB compounds. In autumn 2017, Alma started her PhD at the University of Chemistry and Technology in Prague in the study programme of Drugs and Biomaterials. Her main focus of her PhD is the production of particulate aggregates in the range of hundreds of nanometers in diameter, which can be loaded with different types of drugs and delivered into the human body.

M.Sc. Abhinav Hazarika

Abhinav obtained his Bachelor’s degree in Mechanical Engineering from National Institute of Technology, Silchar, India where he started working on CFD projects in the field of vertical axis wind turbines and blood flow calculation through coronary arteries using commercial software. Thereafter he started his masters at RWTH Aachen University, Germany in the field of computer-aided conception and production in Mechanical Engineering. During this period he worked as a research assistant in Forschungszentrum Jülich GmbH, Jülich from 2015-2017. His responsibilities were to develop CFD model for water gas shift reactor applied in fuel cell technology for Auxilliary Power Units (APUs). His master thesis was concentrated on VOF modeling of two-phase flow inside porous transport layer reconstructed from CT Images. Currently, he will primarily focus on developing improved CFD models for studying flow field in stirred tank bioreactors for his Ph.D.

Ing. Jan Jirat

Jan obatined his Bachelor's and Master's degrees at UCT Prague. He is member of the research group of Miroslav Soos at UCT Prague for over three years. His field of interest is crystal engineering and its application in pharmaceutical industry, namely screening of new crystal forms of active pharmaceutical ingredient (API) – polymorphs, co-crystals, salts and solvates and measurement of their properties, dissolution etc. He also works on scale-up of these crystallization processes and other fields that are connected with crystallization.

Ing. Dan Trunov

Dan started his education in chemistry field at the High School of Chemistry in Prague. He obtained his Bachelor’s degree at University of Chemistry and Technology Prague in 2016 with the main focus on preparation, modification and analysis of porous materials, mainly silica and polystyrene. He has been using different techniques for characterization, such as light scattering and nitrogen adsorption. In 2018 he obtained Master's degree in Chemical Engineering. His master thesis was focused on the stabilization of active pharmaceutical ingredients (APIs) using different suitable polymers. The research was done in cooperation with pharmaceutical company Zentiva Group, a.s. His Ph.D. research is focused on the development of new methods for characterization of turbid suspensions with high concentration of pharmaceutical ingredients. The aim of the research is to find limitations of the different equipments and to find the best methods of analysis using real conditions in the human body for offline analysis.

Master students
Bc. Ondrej Srom
Bc. Katrin Neubauerova
Bc. Jakub Kovacovic
Bc. Ondrej Stoklasa
Bc. Lukas Blaha
Bc. Tereza Bautkinova
Bc. Petr Jelinek
Bc. Anton Iemtsev
Bachelor students
Oskar Marelja
Alumni
Ing. Boleslav Zahradnik
MSc. Hongjin Kim